BrightMEM is an innovative corneal allograft that is transplanted on the ocular surface.
BrightMEM™ Corneal Allograft
The BrightMEM Corneal Allograft
BrightMEM Anterior Keratoplasty (BMAK) is a surgical procedure in which a BrightMEM corneal allograft is transplanted onto the ocular surface. It is made from Descemet's Membrane, which serves as an optimized substrate.
The product is aseptically processed from tissues obtained from donated human tissue (corneas) according to the current Good Tissue Practices (cGTP) regulations established by the US Food & Drug Administration (FDA).
Procedure Overview
Prepare the Patient
Place a speculum in the patient’s eye and debride the epithelium or pannus over the cornea out to a diameter at least 0.5mm wider than the anticipated diameter of the desired allograft. It is important to avoid any overlap of BrightMEM with the peripheral epithelium. Dry the anterior stromal bed thoroughly with a weck cel sponge.
Trephine the BrightMEM Allograft
Trephine the tissue to an appropriate diameter (recommended up to 8.5mm) to fit within the area of epithelial debridement and then discard the scleral rim.
Place the BrightMEM Allograft
Place the trephined corneal button with the BrightMEM allograft side down onto the cornea surface, staying within the margins of the epithelial debridement. Allow the cornea button to dry in place. Peel the anterior corneal button away leaving the BrightMEM allograft in place.
Smooth Out the BrightMEM Allograft
If there are wrinkles in the BrightMEM allograft, use a 30g cannula to gently sweep over or under the graft to smooth it out. After the graft is smooth and its orientation is confirmed, wick residual interface fluid out.
Secure the BrightMEM Allograft
Place tissue fibrin glue over the graft, taking care to completely cover the edges of the graft. Place a bandage contact lens over the glue and carefully remove the lid speculum, without dislodging the contact lens.
